Murphy “Barfi” Johnson (Ranbir Kapoor) is an optimistic , street-wise, charming young man who was born deaf to a Nepali couple in Darjeeling. His mother died when he was a baby and his father raised him alone while working as a chauffeur. Barfi is known as a troublemaker – he cuts lampposts, plays practical jokes on innocent people, and is chased by Sudhanshu Dutta (Saurabh Shukla), a local police officer. Barfi meets Shruti Ghosh (Ileana D’Cruz), who has just arrived in Darjeeling; she is engaged to Ranjeet Sengupta (Jisshu Sengupta) and is due to get married in three months, and Barfi is immediately smitten with Shruti. She also falls in love with Barfi but her mother dissuades her from pursuing him because he could not take care of her with his disabilities and lack of money. Shruti takes her mother’s advice, gets married, and moves to Kolkata, breaking all contact with Barfi.

Uday meets an ambitious and independent girl named Shweta and ends up falling in love with her. After she refuses to date him he sought advice from a love guru.

The story takes place in Panimalai, a hill city, during a spring season. The film begins with RJ Balaji coming to Panimalai to be a guest of a live radio show. In the middle of the show, he starts coughing severely and suddenly loses his voice. He is diagnosed with a new type of virus called the mute flu that causes sudden muteness and sometimes even death.
Aravindh (Dulquer Salman) is a sales representative working with a glue company. His dream is to become a radio jockey, and he even attends interviews with a FM station. As the mute flu spreads across the city, the state government sends Health Minister Sundaralingam (Pandiarajan) to Panimalai to take care of the situation. The people are asked to undergo a medical checkup to check whether they are affected by the virus or not. Aravindh goes to the hospital and meets Anjana (Nazriya Nazim), a junior doctor, who believes that talking is the only cause of all the problems in the world and if people keep things to themselves things will be very fine. Anjana is in a relationship with Vinodh (Abhinav), a possessive guy who always commands her on what she should do and what she should wear. Anjana lives with her father and stepmother Vidhya (Madhoo). Since Anjana lost her mother at a young age, she is reluctant to accept Vidhya as her mother, though she is a sweet and caring woman, and always maintains a distance from her. Vidhya is an aspiring writer who is trying to get her husband’s (Abhishek Shankar) attention and support to write her third book. Her husband finds no time to talk to her as he is too busy with his work.

Iniyan, Rene, Arjun and Madeleine are trying to find themselves and understand their deep-rooted prejudices in life.

Vallavan loves Swapna even though she is three years older than him. Although she reciprocates initially, the age difference and his past with a classmate create tensions in their relationship.

A contract worker in Sudan is abducted by mercenaries and his lover in India awaits his return.

The story of Karthikeyanum Kanamal Pona Kadhaliyum is about a youngster (Deepak) whose lover deserts him and goes away. He befriends another girl (a traffic constable). The rest of the movie is the aftermath of their friendship and other incidents.

Ram’s friends hire Maggie, a call girl, to help him get over his wife, who mistakenly believes him to be a philanderer. However, they get in trouble when Maggie ends up dead.

A young woman posts her pictures online and emails them to a fictitious address; to her surprise, a person actually exists at the address. They meet and eventually fall in love, but a police officer poses trouble because he is interested in the girl.

A charming playboy who has never had a serious relationship finds himself in a spot of bother when he finally meets the right girl. Will they end up together? Or will his fear of commitment affect their relationship?

Prabhu, a happy-go-lucky boy, falls in love with Sandhya who studies in his college. However, difficulties arise when he finds out that she is two years elder to him.

This story begins with Chinna Vandu’s (Dhanush) brothers Paranjothi (Sriman) and Paranthavan (Sathyan), who are not yet married, despite their old age. Chinna Vandu, who studied in his uncle’s son home, falls in love with Vanaroja (Nazriya Nazim), who comes there to visit her grandmother (Sachu) and see the village festival. Chinna Vandu finds many ways to make Vanaroja fall in love, such as making her laugh, but she still does not fall in love with him. During the village festival, Vanaroja’s ring goes missing, so her father Poongavanam (Aadukalam Naren) comes there and tells everyone to find the ring for a reward of 1 lakh. Only Chinna Vandu finds it in front of Vanaroja, but he gives the ring to a poor lady to claim the prize, as Vanaroja does not like him. Seeing this, Vanaroja falls in love with him. Chinna Vandu makes a challenge to himself: to know whether Vanaroja’s in love or not. He gets to know that Vanaroja is also in love with him.
Vanaroja leaves the village to her home but upon reaching, she finds her father has arranged for her engagement with Krishna (Vamsi Krishna) and is getting married with Krishna on her birthday. Chinna Vandu comes to wish her for her birthday on that night and comes to know about the engagement. They both escape from Krishna and his henchmen. Chinna Vandu tells his cousin Soori (Soori) he has eloped with Vanaroja and asks him to come and meet them. Soori tries to find a way for Chinna Vandu to live with Vanaroja, but Chinna Vandu tells him he has already married her. Soori tells them to hide their marriage and go to his family in Kumbukonam. Soori brings Vanaroja to Chinna Vandu’s house, saying she is an orphan. His family accepts her in, but Chinna Vandu’s brothers start to love Vanaroja. Chinna Vandu comes there and makes sure his brothers do not marry her. After some days, their mother (Meera Krishnan) finds that Vanaroja is pregnant and throws her out of the house. Meanwhile, Krishna’s men find Vanaroja and kidnap her. Chinna Vandu finds Vanaroja captured by Krishna and follows him. He goes in a fight and wins, but Chinna Vandu is caught by his whole family, and his father Sambandham (Pyramid Natarajan) does not accept this, but Poongavanam comes and tells Sambandham that his daughter’s life needs to be happy, and so finally he accepts their relationship.