Vijay Rajendran is a happy to-go lucky man. Things change when his father becomes terminally ill, and he is left to manage his business empire.

Two brothers have two different approaches to life. While one brother follows rules and regulations, the other does things his own way.

Vijay Rajendran is a happy to-go lucky man. Things change when his foster father dies unexpectedly.

The film begins with a narration on how India has been turned into a landfill site for domestic and foreign countries, with the countries dumping even ammunition waste onto Indian soil. In Delhi, Balusamy, aka Balu (Arya), a communist leader, is convicted by the court on counts of robbery, murder and treason is given death sentence. Despite Balu’s request to execute him as a martyr by shooting, the court orders that he be hanged within a month’s time by a professional executioner or hangman. He is escorted to a high security prison complex in Chennai by Macaulay (Shaam), an honest, law abiding police officer who is given the charge of monitoring him until his execution. The prison provides freedom to all prisoners, including Balu, to do whatever they want, as long as they do not cause unrest. Balu is instantly admired by the inmates for his patriotism and philosophy as well as his empathy with the inmates. They view him as a spokesperson to the prison officials on behalf of them.

Arjun (Shaam) heads a dance troupe and Priya (Tanu Roy), one of the dancers in the troupe is in love with him. Their aim is to be the permanent fixture at the hotel of Giriprasad (Richard Rishi), a millionaire. They lose the competition but still see their dream realised when the lead dancer in the winning troupe dies. Soon, Giriprasad falls for Priya and his sincerity makes her reciprocate his feelings.

While in the US for training, Tamil Nadu cop Ahkilan bumps into his ex and together they track down a serial killer who has kidnapped an Indian girl.

Krishna (Jayam Ravi) is a happy-go-lucky youth who excels in every field but always does strange and dangerous things to obtain a certain “kick” – a thrill or excitement that he craves. One such activity is secretly double-crossing his childhood friend Dass (Sathyan) while helping him elope. At this point, he meets Nisha (Tamannaah), who is shocked at his recklessness and writes him off as crazy. Krishna sets his sights on Nisha and woos her in a very unorthodox way; he begs her not to fall in love with him. After a host of comical situations involving Krishna’s caring but easygoing parents (Prabhu and Suhasini), local thugs (John Vijay and Mayilsamy), and an ever-present comic relief Jackson (Vadivelu), Nisha accepts Krishna’s love. However, she sets a condition: Krishna must stay in a well-paying job (he had resigned from other jobs due to lack of “kick”), and only then will she agree to marry him. Krishna accepts but soon resigns again for the same reason and tries to hide it from Nisha. When Nisha finds out, she breaks up with him and leaves him for good.

The movie is all about a group of five college friends — Shaam (Shaam), Imaan (Arya), Pooja (Laila), Priya (Asin) and Irene (Pooja). The friends gather for Imaan’s wedding, years after everyone has parted ways.
The movie starts with Pooja leaving USA to go to Imaan’s wedding. Meanwhile, back in India, everyone else is helping Imaan with the preparations for his wedding and catching up with their long lost college friends. The movie goes through series of flashbacks of old memories during their college days. Imaan and Irene meet for the first time, after a long time. The first flashback occurs. They were once in love; however it didn’t turn as Imman had expected it to be.

The story starts with Chandru (Vivek) cheating most people in and around Ooty of their money due to his childish ventures. Though he hails from a rich family, he is unable to maintain the wealth because of his bad luck and unconcerned life style. He has a friend Rakesh (Shaam) who is a farm lord and a rich young man. Chandru saved Rakesh’s life when he spotted him on a roadside accident on the hill side which he uses as a leverage for favours from the kind-hearted Rakesh.
One day Chandru’s grandfather comes to Ooty to stay for two months, thinking that Chandru owns large mansion and lots of land and money. The grandfather who is very rich is an ex-military man. Chandru, afraid to confess the truth to his grandfather, convinces Rakesh to act so that all of Rakesh’s property as his and that Rakesh is his partner but he introduces to them as a manager. Rakesh angered by all this lying threatens to confront Chandru’s relatives but is convinced again by Chandru to stay calm.

Inba (Shaam) is a rough character who works under Priya’s brother (Arun Pandiyan) as a bodyguard of Priya (Sneha).
Priya is a usurious girl, spending most of the time with her friends and absenting herself from the college several times. Hence Arun Pandiyan employa Inba, his faithful servant to guard Priya’s activities. Priya insults him several times since she was not interested in somebody guarding her all the time. However, at one point in the story, Priya is saved by Inba from a gang that is to murder her. The incident develops love in Priya’s heart. Priya exposes her love to Inba where Inba refuses it. In the meantime, Arun Pandiyan comes to know about the love affair and opposes it by beating up Inba.

Unemployed Shakthi Singh lives a poor lifestyle along with his widowed and ailing mother and a sister. His mother falls ill and gets admitted in hospital. While on his way to an interview with HSBC, Shakthi sees a beautiful girl, gets distracted and misses his bus – route No.12B. As a result he misses the interview, and ends up getting employed as a Garage Mechanic with Madan, his friend. He does meet with the same girl, gets to know her name is Jyotika, who lives a wealthy lifestyle with her mother, Sulo, while her dad is away on business. Both continue meeting not aware that her marriage has been arranged with Pratap. This story also depicts the possibility of Shakthi catching the 12B on time, attending the interview and getting hired, pursuing Jyotika in vain, and ending up in the arms of his co-worker, Priya. Both possibilities end up with Shakthi getting involved in a vehicle accident – and no guarantees that he will survive or wed Jyotika.

The film, however, follows familiar pattern of Spanish original, wherein a corpse mysteriously disappears from the city morgue. This leads to summoning of police officer to investigate the case of missing body. As usual needle of suspicion falls on woman’s husband. While Spanish film is noir genre cinema, Ramesh’s Game with its taut and gripping screenplay, is aptly tailored to suit the Indian audience’s palate. How, no-nonsense, smart cop Sharath Chandra unravels the truth; whether high profile lady Maya, has been murdered, is it a case of catalepsy, or case of drunken driving, hit and run, behind it, forms the fulcrum of eerie and edgy Game set in specially constructed forensic lab.

Siva (Shaam) and Sathya (Nithya Das) are college mates and good friends who always look out for each other. Their friendship continues even after their college days. Siva’s and Sathya’s parents mistake their friendship as an affair. The two refuse and make it clear that they are platonic friends with oneness in their thoughts, but no plutonic thoughts. In the course of time, Siva marries Shruthi (Sameksha) and Sathya marries Karthik (Jayasurya). Shruthi soon becomes pregnant but dies of childbirth complciations. Siva is left to raise his son on his own. Many years pass, and Siva’s son (Shyam Ganesh) begins to treat him badly, leaving him destitute. At the same time, Karthik informs Siva that Sathya is in her deathbed due to heart problems. In due course of time, Sathya dies. The film ends as Karthik and Siva, both widowers, walk together, vowing to remain good friends for the remainder of their lives.

Hari (Shaam) and Raji (Sneha) are cousins. Hari gets a job in Chennai. He then comes to Chennai and instead of staying at Raji’s home he rents an apartment with his colleague Vivek. Raji doesn’t like this and refuses to come to Hari’s house until he visits her place. But they meet and catch up with each other now and then. Meanwhile, Hari meets another girl, Swapna (Jaya Re), who plays pranks on people just for fun. During one such prank Hari and Swapna end up becoming friends. They both work in rival Ad agency.While doing a project Hari selects his cousin Raji’s photo (of her eyes) over Swapna’s which makes her upset. But to reconcile their friendship Hari sends Swapna’s pics to Miss Chennai competition which she eventually wins. After a few days Hari, Raji and Swapna coincidentally meet in shopping place where Hari ends up fighting with a person who misbehaved with Raji. Raji gets angry and walks away. Hari drops off Swapna to her house where she proposes to Hari, to which Hari refuses. But he thanks her for making him realise that he is actually in love with his cousin, Raji. Hari apologises to Swapna. Raji goes to attend her childhood friend’s marriage and when she comes back brings along her friend’s brother and also her friend, Bharath (Rajiv Krishna).Bharath had proposed to a girl and when she rejected him, he took to drinking. To make him forget his grief Raji brings him to Chennai. Hari first mistakes that Raji is in love with Bharath.On his birthday, he asks her if she loves Bharath and when she clears off his misunderstanding, he immediately proposes to her. She rejects him.