‘Ramanujan’ is a historical biopic set in early 20th century British India and England, and revolves around the life and times of the mathematical prodigy, Srinivasa Ramanujan. Directed by the award-winning filmmaker Gnana Rajasekaran and with an international cast and crew, ‘Ramanujan’ is a cross-border venture. Considered one of the most romantic stories in the history of mathematics, Ramanujan, a college dropout from a poor family in South India, made extraordinary mathematical discoveries in isolation. He wrote a strange letter filled with theorems and formulas to Prof. Hardy of Trinity College, Cambridge, who immediately identified his genius and invited him to England to conduct further research. ‘Ramanujan’ chronicles the genius’ journey across continents and cultures in search of recognition.

Vasanthi (Bhavana) is the daughter of a man (Lal) who does a lot of help for the refugees. She instantly falls for Jeevan (Jiiva), a Tamil refugee staying in the camp in Rameswaram. Jeevan, nurturing a dream to go back to his homeland, keeps on discouraging the girl, who is stubborn in her love. Jeevan’s heart, influenced by the pure love of the girl, starts melting slowly. Enters Vasanthi’s cousin (Bose Venkat), who is full of dreams on marrying her. He joins as an inspector in the local police station. The whole family is eagerly awaiting their marriage. Problems arise when the family comes to know about the love. Vasanthi’s cousin and his uncle try to eliminate Jeevan. They keep on troubling him, without much success. Meanwhile, the refugees get a chance to go back, and Jeevan has to go with them. He promises Vasanthi that he would come back to marry her. The family is determined to stop him. Vasanthi decides to end her life if Jeevan does not turn up.

A hunchback and a local tough have lookalike love-interests.

The story is told through the protagonist Murugesan (Pasupathy), who recalls his childhood in Virudhunagar town. His father is a butcher who works hard to bring up his four children (two boys and two girls) and have a happy family. Murugesan dotes on his younger brother Kathir, and his weakness, like any other adolescent, is a love for movies (especially MGR films) that are screened in a local theatre. One day, life changes for Murugesan when his father catches him red-handed from the theatre after he bunks school. Murugesan is severely punished and runs away from home, taking money and jewels.
Along the way, Murugesan gets sidetracked from his intended destination of Chennai by an MGR movie poster. He is shown watching several MGR shows, buying a change of clothes, and eating a hearty meal with his ill-gotten money. After spending the night at local temple, he wakes up to find his money and other possessions missing. Murugesan is then taken under the wings of a theatre projectionist in a nearby town. Slowly, the theatre becomes his home.

Surya and Visa fall in love with each other and want to get married. However, when Visa’s mother comes to know about their relationship, she threatens to commit suicide if they stay together.

John Vaseegaran is a young man who ranks fifth richest millionaire in India and 30th on the international level. The plot opens in a graveyard where Vaseegran’s parents’ funeral takes place. He is not disturbed by the demise of his parents as he had not been showered with any affection by them instead concentrated only on making money. A lady of his community expresses her condolence to him and leaves. While getting into her car she finds her diamond ring is missing and screams; the lost ring is in Vaseegaran’s pocket.
Vasee inherits the huge property of his parents and becomes the chairman of 32 companies in his twenties. Though rich he seeks true motherhood affection. He imagines his dream girl and names her Cinderella. He is a Kleptomaniac. He consults his family doctor for a solution. The doctor instructs him to get into love.

A spoiled young heiress marries a poor man in order to inherit her grandfather’s property.

Siva (R. Madhavan) is based out of Srirangam and he comes to Chennai to join a college. He stays with his sister (Anu Hasan) and her husband (Raghuvaran). Siva does not like his brother-in-law and never talks to him, despite several attempts made by his sister to convince both.
Siva meets Priya (Meera Jasmine) during a bus journey, and it is love at first sight for him. He again meets her on a few more occasions and proposes his love, but she warns him to stop following her despite liking him. Siva understands that Priya’s brother Bhaskar (Atul Kulkarni) is a local goon, and he attacks anyone who follows his sister.

Bergmans (Arjun Sarja), a brilliant but unruly student, is thrown out of his seminary for committing the sin of the flesh after being caught red-handed by fellow student Sam Fernando (Arvind Swamy). Blaming the good-hearted Sam for his ouster, Bergmans vows revenge and challenges to prove that evil does reign supreme in this world. Sam finishes his education and training and arrives at a village as the new Father of the local church. A local boy named Thomas of this village who is the illegitimate son of a local fisherman Chetty (Ponvannan) has grown up in a rough neighborhood, following his mother’s death and thus being forced to fend for himself.
Sam takes the rundown church and skeptical villagers in his stride and starts bringing about changes. Through a series of incidents, he also manages to get the unruly Thomas under his control and gets him to learn the tricks of the fishing trade from the villagers. The film fast forwards a few years when Thomas (Gautham Karthik) is grown up and is very close to Sam, who is now a well respected person in the village. Thomas comes across Beatrice (Thulasi Nair) when she is running away from her convent school group who had gotten her admitted to the hospital. They keep running into each other a few times, and Thomas comes to like her presence.

Student in a South Indian college Prabhu is elected as the student leader of the college. When the principal asks him to invite the Governor of the state, Ranjit Singh Rathore, to be the chief guest at the annual day function Prabhu meet up with Ranjit Singh’s daughter, Shruti who happen to be the girl of his dreams. In order to captivate her attention Prabhu join Shruti’s dancing class and is able to impress her thus both fall in love; due to fear of terrorism in the region Shruti is not allow to move without bodyguard. She decides to break this rule in order to run away with Prabhu to a dance festival in Chidambaram only to find life threaten by a bomb that is implanted in that region at that time. But she manages to elude this only to return home whereby her father objects to her relationship with Prabhu and on his behest Prabhu is arrested by the police and accused of planting the bomb in Chidambaram, torture and then later on release. Unknown to the general public Ranjit is involved with a dangerous bomb expert who is responsible for many bomb blasts in the region and Prabhu’s life is under his threat as he has certain evidences that can incarcerate the duo.

Annakodi is in love with a boy who belongs to another caste. When her parents learn about it, they disapprove of the relationship and force her to get married to someone else.

A frustrated and conflicted teenager arrives at a new high school to discover an underground fight club, and meets a classmate who begins to coerce him into fighting.