Satyam begins with Sathyam (Vishal), an assistant police commissioner rescuing a hooligan from encounter thirsty cops, only to arrest him later. He reminds his fellow cops that a cop’s duty is to kill crime not criminals. Sathyam meets his first challenge in tracking a mysterious killer of three ministers. In the process, he finds the culprit Manickvel (Upendra), only to receive a rude shock to know his identity.
For, the murderer is none other than a former police officer, who inspired Sathyam to take the cop job. Revealing the reason behind his change of mind, the ex-cop says that he is on a killing spree as he failed to set right things in khakhi uniform.