After the passing away of her parents in an automobile accident, Radhika moves in to live with her aunt, Malathi, and studies Zoology in Lexicon Science College. She is very friendly with Basu Subtankar and both, along with other girls, create quite a ruckus, much to the chagrin of their teachers and the College Principal. In addition to this, they are also staunch rivals of NRI Geetha Damodar, who wants to be the Student Chair. Radhika competes, there is a tie, but the teachers overturn Radhika’s votes due to many complaints against her, and elect Geetha as the Chair. When Malathi wants Radhika to wed, both girls create a fictional character, name him Ramesh, and tell Malathi that Radhika is in love with Ramesh. Complications arise when a real male named Ramesh surfaces, is subsequently killed, and the duo become suspects amidst a web of deceit and lies created by one of four persons in their lives, namely Malati herself, Geetha, a mysterious woman who sometimes poses as Ramesh’s mother and other times as Geetha’s guardian, and an fourth unknown person – leading the duo to a roller-coaster ride with both the police and the real killer on their tails.

Kandukondain Kandukondain opens with military personnel Major Bala (Mammootty) fighting in a war and losing his left leg in a grenade explosion. After the opening credits, Sowmya (Tabu) and Meenakshi “Meenu” (Aishwarya Rai) are shown as the adult daughters of Padma (Srividya) living in a Chettiar mansion in Karaikudi, Tamil Nadu with their maternal grandfather Chandrasekhar (Unnikrishnan Namboothiri), maidservant Chellatha (S. N. Lakshmi) and younger sister Kamala (Shamili). Sowmya is a school principal while Meenu is passionate about classic Tamil poetry, music and dance. Major Bala, one of the rich men in their village falls in love with Meenu, but Meenu falls in love with Srikanth (Abbas). Manohar (Ajith Kumar) is a director who comes to Meenu’s house for a film shoot. Sowmya and Manohar fall for each other but an issue crops up between the two and whether Manohar manages to win her back forms the rest of their part of the story.

A jealous clerk secretly switches his newborn son with his millionaire friend’s temporarily stillborn son.

A sincere police officer thwarts the vicious plans of a major terrorist by saving some highly confidential documents from falling into the wrong hands.