Krypto the Super-Dog and Superman are inseparable best friends, sharing the same superpowers and fighting crime side by side in Metropolis. However, Krypto must master his own powers for a rescue mission when Superman is kidnapped.

When the Justice League are captured by Lex Luthor, Superman’s dog, Krypto, forms a team of shelter-pets who were given super-powers: A hound named Ace, who becomes super-strong, a pig named PB, who can grow to giant-size, a turtle named Merton, who becomes super-fast, and a squirrel named Chip, who gains electric-powers.